Loïc Comeliau

PhD Researcher

Project Title

Development of enabling technologies to study the interaction between lymphangiogenesis and inflammation

Research Interests

  • In silico modeling
  • Systems biology
  • Dual in vitro/in silico approaches
  • Lymphangiogenesis

Project Summary

Lymphatic vessels have an important role in inflammation and are considered as potential therapeutic targets for inflammatory pathologies. In this project, dual in silico/in vitro approaches will be used to investigate the interplay between lymphangiogenesis and inflammation. We will first develop a virtual lymphatic endothelial cell (LEC) model to investigate the effect of inflammation on the intracellular regulation of the cells. In addition, we will develop an agent-based model representing the LECs, immune actors and the inflamed media interactions. A counterpart in vitro model will be developed using microfluidic chips.

Educational Records

  • Master of Science (MSc) in Biomedical Engineering, 2022
    University of Liège, Belgium
  • Bachelor of Science (BSc) in Engineering, 2020
    University of Liège, Belgium

Contact

lcomeliau[at]uliege.be

Biomechanics Research Unit, GIGA In silico Medicine, University of Liège, CHU-B34, +5. Quartier Hôpital, Avenue de l’Hôpital, 11, 4000 Liège, Belgium.