• Bone regeneration
• 3D printing
• Calcium-phosphate biomaterials

Generally caused by trauma, dental infections, or periodontal diseases, the loss of one or more teeth is accompanied by the resorption of the supporting alveolar bone. The placement of a dental implant therefore requires a procedure called “Guided Bone Regeneration” to fill the alveolar bone defect. This involves the use of a bone substitute and a barrier membrane. In my project, we are developing a synthetic calcium-phosphate-based bone substitute. Using advanced technologies such as in silico modeling, high-resolution 3D printing, and laser surface microtexturing, we adopt a customizable multi-scale design approach to enhance bone regeneration. Within this framework, I am focusing on the in vitro evaluation of the biological properties of these substitutes, exploring how materials, roughness, and structures affect cell behavior.

Graduated as a Biomedical Civil Engineer from the University of Liège (Belgium) in 2023.
Master’s Thesis entitled «Developing osteoarthritis models in mechanically loaded cartilage-on-chips», conducted at the Biomechanics Research Unit (KU Leuven, Belgium).

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margaryta.ivanets [at] uliege.be

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