Sophie Bekisz
Postdoc Researcher
LyMO: Integrated in vitro, in vivo and in silico LYmphangiogenesis Modeling in Osteoarthritis
- In Silico Medicine
- Computational Biology
- In Silico / In Vitro / In vivo loop
- Regulatory Network Modeling
- Lymphangiogenesis
- Osteoarthritis
- Joint inflammation
- Synovial membrane
- Microphysiological systems
- Virtual clinical trial
- Multidisciplinary approach
The LyMO project aims to characterize the crosstalk between osteoarthritis and lymphangiogenesis using integrated in vitro, in vivo, and in silico approaches.
- Graduated as Biomedical Engineer, at the University of Liège (Belgium), in 2018.
- PhD graduation, at ULiège (Belgium), in April 2025.
- Postdoctoral researcher ULiège (Belgium) since May 2025, under FNRS grant since October 2025.
Full list of publications in Orbi
- Marine Gautier-Isola, Marin Truchi, Roger Rezzonico, … Sophie Bekisz, … Roger Rezzonico, “LINC01116, a hypoxia-lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma”, Molecular Oncology, accepted.
- Charles Pottier, Laetitia Montero-Ruiz, … Sophie Bekisz, … Nor Eddine Sounni, “Targeting ferroptosis resistance resensitizes metastatic HR+HER2- breast cancer cells to palbociclib-hormone therapy”, Cancer Commun (Lond), 45(4):460-464, 2025.
- Sébastien Pirson, Marine Gautier-Isola, … Sophie Bekisz, … Agnès Noël, “AXL promotes lymphangiogenesis by amplifying VEGF-C-mediated AKT pathway“, Cellular and Molecular Life Science, Cell. Mol. Life Sci., 82, 95, 2025.
- Sophie Bekisz, Louis Baudin, Florence Buntinx, Agnès Noël, Liesbet Geris, “In Vitro, In Vivo, and In Silico Models of Lymphangiogenesis in Solid Malignancies”, Cancers, 14(6) p. 1525, 2022.
- Sophie Bekisz, Liesbet Geris, “Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications”, Journal of Computational Science, 46:101198, 2020.
- Sophie Bekisz, Lui Holder-Pearson, J. Geoffrey Chase, Thomas Desaive, “In silico validation of a new model-based oral-subcutaneous insulin sensitivity testing through Monte Carlo sensitivity analyses”, Biomedical Signal Processing and Control, 61:102030, 2020.
- Lui Holder Pearson, Sophie Bekisz, Jennifer Knopp, Paul Docherty, J. Geoffrey Chase, Thomas Desaive, “Model-based Modified OGTT Insulin Sensitivity Test design”, IFAC PapersOnLine 51-27 ( 2018 ) 86-91.
sophie.bekisz [at] uliege.be
Biomechanics Research Unit, GIGA In silico Medicine, University of Liège, CHU-B34, +5. Quartier Hôpital, Avenue de l’Hôpital, 11, 4000 Liège, Belgium.