In silico lymphangiogenesis : Development of new tools to generate novel insights in the fundamental mechanisms regulating lymphangiogenesis.
- In Silico Medicine
- Computational Biology
- In Silico / In Vitro / In vivo loop
- Regulatory Network Modeling
My project focuses on the modelling of the process of lymphangiogenesis with mathematical and computational tools. The roles of uPARAP, a newly-discovered key-player in the regulation of Vascular Endothelial Growth Factor Receptors (VEGFRs) involved in lymphangiogenesis, are highlighted. Classical biomedical approaches using in vitro and in vivo models are combined with engineering approaches using in silico (computer) models. This multidisciplinary character enables to better understand the fundamental mechanisms regulating lymphangiogenesis.
- Graduated as Biomedical Engineer, at the University of Liège (Belgium), in 2018.
- Lui Holder Pearson, Sophie Bekisz, Jennifer Knopp, Paul Docherty, J. Geoffrey Chase, Thomas Desaive, “Model-based Modified OGTT Insulin Sensitivity Test design”, IFAC PapersOnLine 51-27 ( 2018 ) 86-91.
sophie.bekisz [at] uliege.be
Biomechanics Research Unit, GIGA In silico Medicine, University of Liège, CHU-B34, +5. Quartier Hôpital, Avenue de l’Hôpital, 11, 4000 Liège, Belgium.