Computational framework for extrusion based 3D bioprinting
- In silico medicine (Computational modeling)
- 3D printing
- 3D imaging and analysis (computed tomography)
One technology frequently used to create tissue-engineering implants, owing to its versatility and scalability, is extrusion-based 3D printing (E3DBP). Substantial (experimental) research has already been performed on E3DBP, but many technical and biological challenges remain to be addressed. The goal of this project is to build a comprehensive E3DBP (finite element) model, of which the simulation results can provide indications for optimal conditions regarding material properties, printability as well as instrument- and cell biology-related parameters. This project will start with an optimisation of printing components such as nozzle configuration and pressure. This will be followed by the formulation of a model for printed multi-layer constructs at macroscale. Finally, a representation of individual cells will be added to the models, quantifying the stresses faced by the cells during and after printing process. The successful modelling of the printing process will provide a useful tool for the further advancement of E3DBP.
- Integrated PhD, Indian Institute of Science (IISc), Bangalore, Karnataka, India.
- Bachelor of Science with Chemistry Honours, Ramakrishna Mission Vidyamandira (Calcutta University), Belur Math, Howrah, West Bengal, India.
- Higher Secondary Education, Uluberia High School, Uluberia, Howrah, West Bengal, India.
- Secondary Education, Uluberia High School, Uluberia, Howrah, West Bengal, India.
Biomechanics Research Unit,
5th floor, Scriptorium,
GIGA In Silico Medicine,
University of Liège, Belgium