In molecular biology, the flow of genetic information is classically described by the Central Dogma, stating that genetic code is transcribed into RNA, which is in turn translated into proteins. These are the functional units which maintain cellular homeostasis and the source of cell type specific functions. However, recent developments in the fields of epigenetics[...]

In silico systems biology aims at using general mathematical and computational tools to get insights into biological and medical questions, mainly through the study of regulatory networks. Different modeling strategies are of concern belonging to causal (mechanistic) or correlation (data driven) families. A few examples of interest in our group are: ordinary and partial differential[...]