The winners of the European Society of Biomechanics (ESB) Mobility award 2022 were announced during the ESB Congress 2022 in Porto (Portugal) and Satanik was one of them. Congratulations, Satanik, well deserved!

During the proposed research stay of two months facilitated by the ESB Mobility Award 2022, Satanik intends to work closely with the group of Prof. Nico Verdonschot in University of Twente, to use a musculoskeletal model developed in his lab to infer about the knee joint kinetics and kinematics for a range of motions both for healthy patients and patients with OA and total knee arthroplasty (TKA). Furthermore, a cartilage on chip system developed in collaboration with Prof. Marcel Karperien in University of Twente will be used to generate relevant experimental data to validate the multiscale model developed by the candidate. This setup is very efficient in not only mimicking the complex multi-axial loading scenario that is experienced in vivo (in the knee joint), but also can be used to test the effect of inflammatory cytokines (such as IL-1 and TNF-α ) on the fate of articular chondrocytes, in combination with mechanical loading. Therefore, this microfluidic setup is a perfect choice to validate the multiscale model that has been developed by the candidate, which is a second objective of the research stay.